Endometriosis & Fertility
Family building can be a challenge, making it a trying and vulnerable moment for many on the journey to parenthood. It shouldn’t have to be so hard to get answers. You can help change that.
Unlocking the differences and overlaps between infertility with and without endometriosis is critical to better answers, earlier interventions, and more compassionate care. At NextGen Jane, we are working to change the way these conditions are studied and diagnosed. Our tampon-based test is working to detect molecular signatures in menstruation, no surgery or extensive medical workup required. By comparing those with infertility linked to endometriosis against those struggling without it, we aim to uncover patterns that traditional methods have missed. You can be part of advancing this research and shaping the future of fertility care.
About the Study
What are we doing?
With 1000s of tampons collected, NextGen Jane is creating the world’s largest menstrual blood biobank. NextGen Jane is using this biobank to develop tampon-based diagnostics for infertility and endometriosis.
Who do we need?
We need to collect tampons from patients who qualify. All participants must reside in the US, have routine menstrual cycles, and have struggled to get pregnant:
- For 12+ months if younger than 35
- For 6+ months if 35 or older
In addition, you must fit one of the following categories:
Endometriosis Confirmed
- You are going in for surgical diagnosis OR
- You have imaging of endometriosis that has not been treated OR
- You have a diagnosis during an unrelated procedure that has not been treated (e.g. C-section) OR
- You have a diagnosis during your last laparoscopy where some or all endometriosis tissue was left untreated
Endometriosis Not Suspected
- You know the reason for your infertility and it is not endometriosis OR
- You were confirmed endo-negative by laparoscopic diagnostic surgery (no tissue was seen) OR
- Your menstrual symptoms do not align with endometriosis
Endometriosis Suspected/Post-Lap (Enrolling with Low Priority):
- You have been diagnosed with endometriosis via your last laparoscopy where all tissue was removed OR
- You suspect endometriosis
What do we need from you?
Your participation can transform an often-overlooked aspect of women’s health by utilizing something that is normally discarded.
- Intake call: We’ll ask you to schedule a 30-minute informed consent call to review study details and introduce you to NGJ
- Collections: We’ll ask you to collect 3 tampons per cycle, across at least one menstrual cycle, with the possibility of additional collections. Collections are done at home with mail-in kits.
- Questionnaires: You’ll also complete brief questionnaires designed to better understand your health background and menstrual experiences, including any previous pregnancies or health conditions.
- Medical Records: For some participants, we’ll also request access to paperwork detailing infertility or endometriosis diagnosis, IUI/IVF protocols, imaging reports, or fertility blood panels.
- Additional Contact: After your first collection cycle, we ask you to remain open to being contacted for additional collection and data asks for up to 2 years.
What will you receive for participating?
To acknowledge your contribution, you will receive a $25 digital Amazon gift card for each tampon provided, up to a study maximum of $500.
Together, we can revolutionize how reproductive health conditions are diagnosed and managed. Thank you for helping to reshape healthcare for the next generation.
You can be a part of our study to establish how well our test works for people struggling with infertility.
